00402nas a2200109 4500008004100000245009200041210006900133260000800202300001400210490000700224856006100231 2023 eng d00aControlling light propagation in multimode fibers for imaging, spectroscopy, and beyond0 aControlling light propagation in multimode fibers for imaging sp cJun a524–6120 v15 uhttps://opg.optica.org/aop/abstract.cfm?URI=aop-15-2-52400422nas a2200109 4500008004100000022001400041245009800055210006900153300000600222490000600228856007800234 2022 eng d a2689-962000aHybrid multimode - multicore fibre based holographic endoscope for deep-tissue neurophotonics0 aHybrid multimode multicore fibre based holographic endoscope for a10 v3 uhttps://www.light-am.com//article/id/5e7e4e57-462a-4c48-92ca-1aec395fed5900346nas a2200109 4500008004100000245005100041210005100092260000800143300001800151490000700169856006000176 2022 eng d00aNear perfect focusing through multimode fibres0 aNear perfect focusing through multimode fibres cMar a10645–106630 v30 uhttp://opg.optica.org/oe/abstract.cfm?URI=oe-30-7-1064500333nas a2200085 4500008004100000245008500041210006900126490000600195856004600201 2022 eng d00aNeurophotonic tools for microscopic measurements and manipulation: status report0 aNeurophotonic tools for microscopic measurements and manipulatio0 v9 uhttps://doi.org/10.1117/1.NPh.9.S1.01300100917nas a2200121 4500008004100000245006700041210006700108260000800175300001100183490000600194520054700200856004800747 2022 eng d00aRoadmap on wavefront shaping and deep imaging in complex media0 aRoadmap on wavefront shaping and deep imaging in complex media caug a0425010 v43 a
The last decade has seen the development of a wide set of tools, such as wavefront shaping, computational or fundamental methods, that allow us to understand and control light propagation in a complex medium, such as biological tissues or multimode fibers. A vibrant and diverse community is now working in this field, which has revolutionized the prospect of diffraction-limited imaging at depth in tissues. This roadmap highlights several key aspects of this fast developing field, and some of the challenges and opportunities ahead.
uhttps://dx.doi.org/10.1088/2515-7647/ac76f900906nas a2200121 4500008004100000245005100041210005000092260000800142300001800150490000700168520054400175856006500719 2021 eng d00aAll-optical manipulation of photonic membranes0 aAlloptical manipulation of photonic membranes cMay a14260–142680 v293 aWe demonstrate the all-optical manipulation of polymeric membranes in microfluidic environments. The membranes are decorated with handles for their use in holographic optical tweezers systems. Our results show that due to their form factor the membranes present a substantial increase in their mechanical stability, respect to micrometric dielectric particles. This intrinsic superior stability is expected to improve profoundly a wide range of bio-photonic applications that rely on the optical manipulation of micrometric objects.
uhttp://www.opticsexpress.org/abstract.cfm?URI=oe-29-10-1426000438nas a2200109 4500008004100000245011700041210006900158260000800227300001800235490000700253856006800260 2021 eng d00aComputational image enhancement of multimode fibre-based holographic endo-microscopy: harnessing the muddy modes0 aComputational image enhancement of multimode fibrebased holograp cNov a38206–382200 v29 uhttp://www.osapublishing.org/oe/abstract.cfm?URI=oe-29-23-3820601747nas a2200109 4500008004100000245008100041210006900122300001800191490000700209520135300216856006801569 2021 eng d00aSide-view holographic endomicroscopy via a custom-terminated multimode fibre0 aSideview holographic endomicroscopy via a customterminated multi a23083–230950 v293 aMicroendoscopes based on optical fibres have recently come to the fore as promising candidates allowing in-vivo observations of otherwise inaccessible biological structures in animal models. Despite being still in its infancy, imaging can now be performed at the tip of a single multimode fibre, by relying on powerful holographic methods for light control. Fibre based endoscopy is commonly performed en face, resulting in possible damage of the specimen owing to the direct contact between the distal end of the probe and target. On this ground, we designed an all-fibre probe with an engineered termination that reduces compression and damage to the tissue under investigation upon probe insertion. The geometry of the termination brings the field of view to a plane parallel to the fibre&\#x2019;s longitudinal direction, conveying the probe with off-axis imaging capabilities. We show that its focusing ability also benefits from a higher numerical aperture, resulting in imaging with increased spatial resolution. The effect of probe insertion was investigated inside a tissue phantom comprising fluorescent particles suspended in agarose gel, and a comparison was established between the novel side-view probe and the standard en face fibre probe. This new concept paves the way to significantly less invasive deep-tissue imaging.
uhttp://www.osapublishing.org/oe/abstract.cfm?URI=oe-29-15-2308300405nas a2200109 4500008004100000245008400041210006900125260000800194300001800202490000700220856006800227 2021 eng d00aThermal stability of wavefront shaping using a DMD as a spatial light modulator0 aThermal stability of wavefront shaping using a DMD as a spatial cDec a41808–418180 v29 uhttp://www.osapublishing.org/oe/abstract.cfm?URI=oe-29-25-4180801787nas a2200109 4500008004100000245006100041210006000102300001800162490000700180520142200187856006801609 2021 eng d00aTime-averaged image projection through a multimode fiber0 aTimeaveraged image projection through a multimode fiber a28005–280200 v293 aMany disciplines, ranging from lithography to opto-genetics, require high-fidelity image projection. However, not all optical systems can display all types of images with equal ease. Therefore, the image projection quality is dependent on the type of image. In some circumstances, this can lead to a catastrophic loss of intensity or image quality. For complex optical systems, it may not be known in advance which types of images pose a problem. Here we show a new method called Time-Averaged image Projection (TAP), allowing us to mitigate these limitations by taking the entire image projection system into account despite its complexity and building the desired intensity distribution up from multiple illumination patterns. Using a complex optical setup, consisting of a wavefront shaper and a multimode optical fiber illuminated by coherent light, we succeeded to suppress any speckle-related background. Further, we can display independent images at multiple distances simultaneously, and alter the effective sharpness depth through the algorithm. Our results demonstrate that TAP can significantly enhance the image projection quality in multiple ways. We anticipate that our results will greatly complement any application in which the response to light irradiation is relatively slow (one microsecond with current technology) and where high-fidelity spatial distribution of optical power is required.
uhttp://www.osapublishing.org/oe/abstract.cfm?URI=oe-29-18-2800500325nas a2200097 4500008004100000245006300041210006100104300001400165490000800179856004000187 2021 eng d00aTime-of-flight 3D imaging through multimode optical fibers0 aTimeofflight 3D imaging through multimode optical fibers a1395-13990 v374 uhttps://www.isibrno.cz/en/node/349801177nas a2200109 4500008004100000245006700041210006600108300001800174490000700192520080300199856006501002 2019 eng d00aLabel-free CARS microscopy through a multimode fiber endoscope0 aLabelfree CARS microscopy through a multimode fiber endoscope a30055–300660 v273 aMultimode fibres have recently been employed as high-resolution ultra-thin endoscopes, capable of imaging biological structures deep inside tissue in vivo. Here, we extend this technique to label-free non-linear microscopy with chemical contrast using coherent anti-Stokes Raman scattering (CARS) through a multimode fibre endoscope, which opens up new avenues for instant and in-situ diagnosis of potentially malignant tissue. We use a commercial 125 &\#x00B5;m diameter, 0.29 NA GRIN fibre, and wavefront shaping on an SLM is used to create foci that are scanned behind the fibre facet across the sample. The chemical selectivity is demonstrated by imaging 2 &\#x00B5;m polystyrene and 2.5 &\#x00B5;m PMMA beads with per pixel integration time as low as 1 ms for epi-detection.
uhttp://www.opticsexpress.org/abstract.cfm?URI=oe-27-21-3005500377nas a2200109 4500008004100000245006400041210006400105260000800169300001800177490000700195856006500202 2019 eng d00aNanobore fiber focus trap with enhanced tuning capabilities0 aNanobore fiber focus trap with enhanced tuning capabilities cDec a36221–362300 v27 uhttp://www.opticsexpress.org/abstract.cfm?URI=oe-27-25-3622101094nas a2200109 4500008004100000245007300041210006900114300001800183490000700201520071100208856006500919 2019 eng d00aWavelength dependent characterization of a multimode fibre endoscope0 aWavelength dependent characterization of a multimode fibre endos a28239–282530 v273 aMultimode fibres have recently shown promise as miniature endoscopic probes. When used for non-linear microscopy, the bandwidth of the imaging system limits the ability to focus light from broadband pulsed lasers as well as the possibility of wavelength tuning during the imaging. We demonstrate that the bandwidth is limited by the dispersion of the off-axis hologram displayed on the SLM, which can be corrected for, and by the limited bandwidth of the fibre itself. The selection of the fibre is therefore crucial for these experiments. In addition, we show that a standard prism pulse compressor is sufficient for material dispersion compensation for multi-photon imaging with a fibre endoscope.
uhttp://www.opticsexpress.org/abstract.cfm?URI=oe-27-20-2823900342nas a2200097 4500008004100000245008100041210006900122300000700191490000600198856004000204 2018 eng d00aHigh-fidelity multimode fibre-based endoscopy for deep brain in vivo imaging0 aHighfidelity multimode fibrebased endoscopy for deep brain in vi a920 v7 uhttps://www.isibrno.cz/en/node/298500376nas a2200097 4500008004100000245010500041210006900146300001500215490000800230856004000238 2018 eng d00aRobustness of Light-Transport Processes to Bending Deformations in Graded-Index Multimode Waveguides0 aRobustness of LightTransport Processes to Bending Deformations i a233901:1-50 v120 uhttps://www.isibrno.cz/en/node/298400380nas a2200097 4500008004100000245011800041210006900159300000800228490000600236856004000242 2018 eng d00aSubcellular spatial resolution achieved for deep-brain imaging in vivo using a minimally invasive multimode fiber0 aSubcellular spatial resolution achieved for deepbrain imaging in a1100 v7 uhttps://www.isibrno.cz/en/node/298600383nas a2200097 4500008004100000245011600041210006900157300001200226490000700238856004000245 2018 eng d00aThree-dimensional holographic optical manipulation through a high-numerical-aperture soft-glass multimode fibre0 aThreedimensional holographic optical manipulation through a high a33–390 v12 uhttps://www.isibrno.cz/en/node/298300371nas a2200097 4500008004100000245010500041210006900146300001200215490000600227856004000233 2013 eng d00aExperimental demonstration of optical transport, sorting and self-arrangement using a `tractor beam'0 aExperimental demonstration of optical transport sorting and self a123-1270 v7 uhttps://www.isibrno.cz/en/node/304200342nas a2200097 4500008004100000245007500041210006900116300001100185490000800196856004000204 2012 eng d00aSpeed enhancement of multi-particle chain in a traveling standing wave0 aSpeed enhancement of multiparticle chain in a traveling standing a0511030 v100 uhttps://www.isibrno.cz/en/node/304900331nas a2200097 4500008004100000245006700041210006700108300001100175490000700186856004000193 2011 eng d00aDynamic size tuning of multidimensional optically bound matter0 aDynamic size tuning of multidimensional optically bound matter a1011050 v99 uhttps://www.isibrno.cz/en/node/305300355nas a2200097 4500008004100000245008900041210006900130300001200199490000600211856004000217 2011 eng d00aThe holographic optical micro-manipulation system based on counter-propagating beams0 aholographic optical micromanipulation system based on counterpro a50–560 v8 uhttps://www.isibrno.cz/en/node/305400372nas a2200109 4500008004100000022001400041245007300055210006900128300001800197490000700215856004000222 2010 eng d a1094-408700aExperimental and theoretical determination of optical binding forces0 aExperimental and theoretical determination of optical binding fo a25389–254020 v18 uhttps://www.isibrno.cz/en/node/306000332nas a2200097 4500008004100000245006500041210006300106300001800169490000700187856004000194 2008 eng d00aHigh quality quasi-Bessel beam generated by round-tip axicon0 aHigh quality quasiBessel beam generated by roundtip axicon a12688–127000 v16 uhttps://www.isibrno.cz/en/node/306600342nas a2200109 4500008004100000022001400041245006000055210005800115300001100173490000800184856004000192 2008 eng d a0031-900700aLong-range one-dimensional longitudinal optical binding0 aLongrange onedimensional longitudinal optical binding a1436010 v101 uhttps://www.isibrno.cz/en/node/307000343nas a2200109 4500008004100000022001400041245005700055210005700112300001700169490000700186856004000193 2008 eng d a0003-695100aStatic optical sorting in a laser interference field0 aStatic optical sorting in a laser interference field a161110:1–30 v92 uhttps://www.isibrno.cz/en/node/306800389nas a2200109 4500008004100000022001400041245009700055210006900152300001100221490000700232856004000239 2008 eng d a1367-263000aSurface delivery of a single nanoparticle under moving evanescent standing-wave illumination0 aSurface delivery of a single nanoparticle under moving evanescen a1130100 v10 uhttps://www.isibrno.cz/en/node/306900318nas a2200097 4500008004100000245005900041210005900100300001400159490000700173856004000180 2007 eng d00aCellular and colloidal separation using optical forces0 aCellular and colloidal separation using optical forces a467–4950 v82 uhttps://www.isibrno.cz/en/node/307100361nas a2200097 4500008004100000245009000041210006900131300001600200490000700216856004000223 2007 eng d00aOptical tracking of spherical micro-objects in spatially periodic interference fields0 aOptical tracking of spherical microobjects in spatially periodic a2262–22720 v15 uhttps://www.isibrno.cz/en/node/307200340nas a2200097 4500008004100000245007100041210006900112300001400181490000700195856004000202 2006 eng d00aFormation of long and thin polymer fiber using nondiffracting beam0 aFormation of long and thin polymer fiber using nondiffracting be a8506-85150 v14 uhttps://www.isibrno.cz/en/node/307800376nas a2200097 4500008004100000245010700041210006900148300001400217490000700231856004000238 2006 eng d00aOptical forces generated by evanescent standing waves and their usage for sub-micron particle delivery0 aOptical forces generated by evanescent standing waves and their a157–1650 v84 uhttps://www.isibrno.cz/en/node/308000319nas a2200097 4500008004100000245006100041210005800102300001400160490000700174856004000181 2006 eng d00aAn optical nanotrap array movable over a milimetre range0 aoptical nanotrap array movable over a milimetre range a197–2030 v84 uhttps://www.isibrno.cz/en/node/307900354nas a2200097 4500008004100000245008400041210006900125300001500194490000700209856004000216 2006 eng d00aOptical sorting and detection of sub-micron objects in a motional standing wave0 aOptical sorting and detection of submicron objects in a motional a035105:1-60 v74 uhttps://www.isibrno.cz/en/node/308200339nas a2200097 4500008004100000245007800041210006900119300000700188490000600195856004000201 2006 eng d00aSub-micron particle organization by self-imaging of non-diffracting beams0 aSubmicron particle organization by selfimaging of nondiffracting a430 v8 uhttps://www.isibrno.cz/en/node/308300330nas a2200097 4500008004100000245006000041210006000101300002400161490000700185856004000192 2005 eng d00aOptical conveyor belt for delivery of submicron objects0 aOptical conveyor belt for delivery of submicron objects a174101-1–174101-30 v86 uhttps://www.isibrno.cz/en/node/3085