TY - JOUR T1 - Neurophotonic tools for microscopic measurements and manipulation: status report JF - Neurophotonics Y1 - 2022 A1 - Ahmed Abdelfattah A1 - Sapna Ahuja A1 - Taner Akkin A1 - Srinivasa Rao Allu A1 - David A. Boas A1 - Joshua Brake A1 - Erin M. Buckley A1 - Robert E. Campbell A1 - Anderson I. Chen A1 - Xiaojun Cheng A1 - Tomáš Čižmár A1 - Irene Costantini A1 - Massimo De Vittorio A1 - Anna Devor A1 - Patrick R. Doran A1 - Mirna El Khatib A1 - Valentina Emiliani A1 - Natalie Fomin-Thunemann A1 - Yeshaiahu Fainman A1 - Tomás Fernández Alfonso A1 - Christopher G. L. Ferri A1 - Ariel Gilad A1 - Xue Han A1 - Andrew Harris A1 - Elizabeth M. C. Hillman A1 - Ute Hochgeschwender A1 - Matthew G. Holt A1 - Na Ji A1 - Kivilcim Kiliç A1 - Evelyn M. R. Lake A1 - Lei Li A1 - Tianqi Li A1 - Philipp Mächler A1 - Rickson C. Mesquita A1 - Evan W. Miller A1 - K.M. Naga Srinivas Nadella A1 - U. Valentin Nägerl A1 - Yusuke Nasu A1 - Axel Nimmerjahn A1 - Petra Ondráčková A1 - Francesco S. Pavone A1 - Citlali Perez Campos A1 - Darcy S. Peterka A1 - Filippo Pisano A1 - Ferruccio Pisanello A1 - Francesca Puppo A1 - Bernardo L. Sabatini A1 - Sanaz Sadegh A1 - Sava Sakadžic A1 - Shy Shoham A1 - Sanaya N. Shroff A1 - R. Angus Silver A1 - Ruth R. Sims A1 - Spencer L. Smith A1 - Vivek J. Srinivasan A1 - Martin Thunemann A1 - Lei Tian A1 - Lin Tian A1 - Thomas Troxler A1 - Antoine Valera A1 - Alipasha Vaziri A1 - Sergei A. Vinogradov A1 - Flavia Vitale A1 - Lihong V. Wang A1 - Hana Uhlířová A1 - Chris Xu A1 - Changhuei Yang A1 - Mu-Han Yang A1 - Gary Yellen A1 - Ofer Yizhar A1 - Yongxin Zhao KW - KF KW - MF VL - 9 UR - https://doi.org/10.1117/1.NPh.9.S1.013001 ER - TY - JOUR T1 - Side-view holographic endomicroscopy via a custom-terminated multimode fibre JF - Opt. Express Y1 - 2021 A1 - Beatriz M. Silveira A1 - Tomáš Pikálek A1 - Miroslav Stibůrek A1 - Petra Ondráčková A1 - Petr Jákl A1 - Ivo T. Leite A1 - Tomáš Čižmár KW - KF KW - MF AB -

Microendoscopes based on optical fibres have recently come to the fore as promising candidates allowing in-vivo observations of otherwise inaccessible biological structures in animal models. Despite being still in its infancy, imaging can now be performed at the tip of a single multimode fibre, by relying on powerful holographic methods for light control. Fibre based endoscopy is commonly performed en face, resulting in possible damage of the specimen owing to the direct contact between the distal end of the probe and target. On this ground, we designed an all-fibre probe with an engineered termination that reduces compression and damage to the tissue under investigation upon probe insertion. The geometry of the termination brings the field of view to a plane parallel to the fibre&\#x2019;s longitudinal direction, conveying the probe with off-axis imaging capabilities. We show that its focusing ability also benefits from a higher numerical aperture, resulting in imaging with increased spatial resolution. The effect of probe insertion was investigated inside a tissue phantom comprising fluorescent particles suspended in agarose gel, and a comparison was established between the novel side-view probe and the standard en face fibre probe. This new concept paves the way to significantly less invasive deep-tissue imaging.

VL - 29 UR - http://www.osapublishing.org/oe/abstract.cfm?URI=oe-29-15-23083 ER -